Brii Biosciences
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Brii Biosciences

http://www.briibio.com/
Last activity: 21.08.2026
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Categories: BioTechHepatitisBImmunotherapyPharmaceuticalsR&D
Brii Biosciences (Brii Bio) is a company committed to serving patients’ needs and improving public health in China. Founded in early 2018, the company focuses on accelerating innovation and optimizing access to the latest medicines for Chinese patients. Brii Bio helps global partners drive growth and improve return on investment through better understanding of Chinese healthcare systems and access to the world’s second largest pharmaceutical market. The company’s focus is treatments for chronic illnesses with significant burdens, including infectious diseases, liver and lung diseases, and other illnesses. The company is headquartered in the People’s Republic of China and the United States, with offices in Shanghai, Beijing, San Francisco, and Durham, North Carolina.
Website visits
9.5K /mo.
Mentions
94
Location: China
Employees: 51-200
Total raised: $415M
Founded date: 2018

Investors 5

Funding Rounds 2

DateSeriesAmountInvestors
23.03.2021Series C$155M-
25.05.2018-$260M-

Mentions in press and media 94

DateTitleDescription
21.08.2026Brii Biosciences Provides Corporate Updates and Reports 2026 Interim Financial ResultsTopline Data from Phase 2b Studies Inform HBV Functional Cure Strategy; Additional Data Expected in 2H 2026 Emerging Discovery Programs Build Momentum BRII-5395 mRNA Cancer Vaccine Moving into Clinical Evaluation for HCC Strong Cash Positio...
03.07.2026Brii Bio Announces Topline End-of-Treatment Data from Phase 2b ENRICH and ENHANCE Studies for the Treatment of Chronic Hepatitis BEnd-of-treatment data from ENRICH demonstrated higher HBsAg loss rates, consistent with ENSURE Cohort 4, confirming the role of BRII-179 in priming immune responses for functional cure strategies End-of-treatment data from ENHANCE did not d...
27.05.2026Brii Bio Presents Late-Breaking Data from Its Phase 2 ENSURE Study at EASL Congress 2026, Further Supporting the Potential Role of BRII-179 in Achieving Durable Immunological Control of HBV- Final results from the ENSURE study demonstrate that the addition of elebsiran resulted in a higher functional cure rate compared with pegylated interferon alfa (PEG-IFNα) alone - Data from Cohort 4 suggested that participants responding ...
26.04.2026Brii Bio Presents Cross-Study Analysis of Post-Treatment HBsAg Rebound at APASL 2026- Participants achieving HBsAg loss with pegylated interferon alfa (PEG-IFNα) ± elebsiran or BRII-179 demonstrated favorable off-treatment clinical outcomes, with most HBsAg rebounds
19.03.2026Brii Biosciences Provides Corporate Updates and Reports Full Year 2025 Financial ResultsAdvancing HBV Functional Cure Toward Key Phase 2b Data Readouts Increasing Discovery Efforts to Drive Long-term Value Creation Strong Cash Position Supporting Strategic Priorities Upcoming Conference Calls: English Session: March 20 at 8:30...
10.11.2025Brii Biosciences Presents Late-Breaking Data from Ongoing Phase 2 ENSURE Study at AASLD 2025, Reinforcing BRII-179's Potential as a Curative Treatment for Chronic Hepatitis BCohort 4 follow-up confirms durable hepatitis B surface antigen (HBsAg) loss at 24 weeks post end of treatment (EOT) in BRII-179 anti-HBs responders treated with elebsiran plus pegylated interferon alfa (PEG-IFNα) Data suggest the potential...
07.11.2025Brii Biosciences Announces Publication of Phase 2 ENSURE Study Results in Nature MedicineFindings provide scientific insights into the contribution of small interfering RNA (siRNA) and therapeutic vaccination towards the HBV functional cure strategy DURHAM, N.C. and BEIJING, Nov. 7, 2025 /PRNewswire/ -- Brii Biosciences Limited...
21.08.2025Brii Biosciences Provides Corporate Updates and Reports 2025 Interim Financial ResultsMultiple Ongoing Phase 2b Studies Advancing HBV Functional Cure Strategy Greater China Partnership with Joincare to Accelerate Development of Critical Care Antibiotic soralimixin Strong Cash Position to Pursue New Discovery Opportunities an...
04.07.2025Brii Biosciences Announces Licensing Agreement with Joincare Group for Rights to BRII-693 in Greater ChinaJoincare Group to lead the clinical development and commercialization of BRII-693 in Greater China Brii Biosciences retains ex-Greater China rights to address the global antimicrobial resistance threats and continues investment in other pri...
08.05.2025Brii Bio Presents Late-Breaking Data from Its Ongoing Phase 2 ENSURE Study at EASL Congress 2025, Suggesting BRII-179's Role in Advancing Higher HBsAg LossEnd of treatment (EOT) data from Cohort 4 of the ENSURE study suggest that patients responding to prior BRII-179 treatment achieved faster and higher rate of surface antigen clearance with curative treatments compared to BRII-179 naïve part...
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