The core technology employed by the OrganOx metra® has been in development for over 15 years. During this time both of the founders (Professor Peter Friend and Professor Constantin Coussios) have driven the development of organ preservation and maintenance, formerly at the University of Cambridge and latterly at the University of Oxford.
OrganOx Limited was founded in April 2008 as a spin-out from the University of Oxford.
Conventional cold preservation involves storage of the liver at 4˚C, using a non-physiological perfusion solution that aims to minimise liver decay. By contrast, warm preservation seeks to re-create an environment that mimics the human body by continuously perfusing at physiological pressures and flows with oxygen-carrying red cells at 37˚C and providing nutrition. The liver is therefore functional during the preservation period, producing bile, metabolizing glucose and maintaining a physiological pH. This enables objective assessment of organ performance prior to transplant, extended preservation times, and the potential use of organs that are presently being discarded.
OrganOx Limited was founded in April 2008 as a spin-out from the University of Oxford.
Conventional cold preservation involves storage of the liver at 4˚C, using a non-physiological perfusion solution that aims to minimise liver decay. By contrast, warm preservation seeks to re-create an environment that mimics the human body by continuously perfusing at physiological pressures and flows with oxygen-carrying red cells at 37˚C and providing nutrition. The liver is therefore functional during the preservation period, producing bile, metabolizing glucose and maintaining a physiological pH. This enables objective assessment of organ performance prior to transplant, extended preservation times, and the potential use of organs that are presently being discarded.
Phone: +44 1865 784156
Total raised: $180.72M
Founded date: 2008
Investors 5
| Date | Name | Website |
| - | Amadeus Ca... | amadeuscap... |
| - | Oxford Uni... | innovation... |
| - | Oxford Inv... | oxfordinve... |
| - | Perivoli I... | perivoliin... |
| - | BGF Ventur... | bgf.co.uk |
Funding Rounds 3
| Date | Series | Amount | Investors |
| 24.02.2025 | - | $142M | - |
| 17.07.2023 | IPO | $32.7M | - |
| 08.01.2020 | - | $6.03M | BGF Ventur... |
Mentions in press and media 22
| Date | Title | Description |
| 16.09.2026 | Government plots university spinout crackdown | The government is plotting to clamp down on the number university spinouts that shift their operations abroad or float overseas, the boss of the body responsible for research investment has said, in a move likely to spark unrest among found... |
| 07.06.2026 | Upgrading the grid risks ending up like HS2 | Upgrading the UK’s electricity grid is a vastly complex project. I hope the government’s learned from HS2, writes John Lazar The GB electricity system is being upgraded in line with the UK’s Clean Power 2030 target to accommodate a vast inc... |
| 19.05.2026 | Lauxera Capital Partners: €520 Million Fund Raised For European Healthtech Expansion | Lauxera Capital Partners announced the successful close of its Lauxera Growth II fund at €520 million, surpassing its €500 million hard cap and nearly doubling the size of the firm’s debut fund. The oversubscribed fund was finalized less th... |
| 19.09.2025 | Startup Funding: Luke Rajah, BGF Early Stage Partner, Deep Tech and Life Sciences Luke Rajah is a Partner at BGF, focused on early-stage investments in deep tech and life sciences — two sectors where ... | From pioneering medtech breakthroughs to next-generation semiconductors, Rajah works closely with ambitious founders tackling some of the world's toughest challenges. In this Entrepreneur UK interview, he shares practical insights for early... |
| 10.09.2025 | British Business Bank CEO on BBB’s investor credentials, Sheffield HQ, and paying “civil service” salaries | Louis Taylor, the CEO of the British Business Bank (BBB), the UK’s biggest venture investor, has just come back from holiday, where he says he has “tried to shed” some excess weight amassed by the many corporate breakfasts and dinners he at... |
| 03.09.2025 | A 0.5 per cent pension shift could secure Britain’s tech supremacy | To solve the UK’s struggle to scale its world-class startups, we must unlock the nation’s vast pension funds for venture capital investment to fuel domestic growth and ensure technological sovereignty, says Dame Anne Glover This week, as le... |
| 30.08.2025 | European Tech Accelerates: HealthTech Leads, AI Drives Innovation, and Strategic Acquisitions Reshape Markets | European tech thrives. Ortivity secured €200M for German orthopaedic care expansion, a major HealthTech boost. Significant funding rounds propelled diverse sectors, like Framer's $100M raise. Key acquisitions reshaped the market, including ... |
| 29.08.2025 | Ortivity lands €200M to grow orthopaedic clinics, CrowdStrike acquires Spanish startup Onum, and Bitpanda snubs London | This week we tracked more than 55 tech funding deals worth over €658 million, and over 15 exits, M&A transactions, rumours, and related news stories across Europe. If email is more your thing, you can always subscribe to our newsletter ... |
| 25.08.2025 | Oxford-based OrganOx achieves one of the UK’s largest medtech exits at $1.5 billion valuation | OrganOx, an Oxford-based medtech company that developed technology to preserve donor livers outside the human body, has been acquired in a deal valued at $1.5 billion. This marks one of the UK’s largest medtech exits and delivers £175 milli... |
| 25.08.2025 | Oxford spinout OrganOx acquired by Terumo for $1.5 billion, largest university spinout exit in UK history | OrganOx, the Oxford University spinout that has been quietly reshaping the field of organ transplantation, is being acquired by Tokyo-based Terumo Corporation in a $1.5 billion deal — the largest acquisition of a university spinout in the U... |
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