SilcsBio provides software and services for unlocking the full potential of computer driven drug design. Our algorithms for mapping proteins will provide you with a level of detail you have never before experienced. From our highly accurate free energy maps to conformational nuances revealing hidden pockets of opportunity, you will discover a whole new world of possibilities.
Our main products are:
SILCS (Site-Identification by Ligand Competitive Saturation): provides sophisticated chemical functional group mapping for proteins and other biological targets, yielding 3-D maps and quantitative data to assist in ligand design and optimization. Possible applications include: Database Screening, Ligand, Optimization, Fragment-based Ligand Design, and Pharmacophore Generation.
Single Step FEP: Single Step free Energy Perturbation allows free energy calculations 1,000 times faster than with standard FEP. Evaluate thousands of ligand modifications per hour without compromising accuracy.
CGenFF: The CHARMM General Force Field program generates comprehensive parameters and topology information for a wide range of drug-like molecules,.allowing their use in Computer-Aided Drug Design campaigns.
Our main products are:
SILCS (Site-Identification by Ligand Competitive Saturation): provides sophisticated chemical functional group mapping for proteins and other biological targets, yielding 3-D maps and quantitative data to assist in ligand design and optimization. Possible applications include: Database Screening, Ligand, Optimization, Fragment-based Ligand Design, and Pharmacophore Generation.
Single Step FEP: Single Step free Energy Perturbation allows free energy calculations 1,000 times faster than with standard FEP. Evaluate thousands of ligand modifications per hour without compromising accuracy.
CGenFF: The CHARMM General Force Field program generates comprehensive parameters and topology information for a wide range of drug-like molecules,.allowing their use in Computer-Aided Drug Design campaigns.
Location: United States, Maryland, Baltimore
Employees: 1-10
Total raised: $1.8M
Founded date: 2012
Investors 2
| Date | Name | Website |
| - | UM Venture... | umventures... |
| - | Early Char... | earlycharm... |
Funding Rounds 1
| Date | Series | Amount | Investors |
| 16.11.2021 | - | $1.8M | - |
Mentions in press and media 1
| Date | Title | Description |
| 16.07.2018 | SilcsBio’s drug design algorithms get patent | Algorithms used in a Spark Baltimore–based company’s software was recently patented for algorithms that will help it expand its presence in the market, according to its CEO. SilcsBio is bringing software to the pharmaceutical process of fin... |